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A national evaluation of opioid prescribing and persistent use after ambulatory anorectal surgery

  • Over 2% of ambulatory anorectal procedures develop new persistent opioid use.
  • Logistic regression found new persistent opioid use was associated with perioperative opioid fills, increased comorbidity, tobacco use, and pain disorders; there was no significant association with procedure performed.
  • Despite small annual reductions in opioid prescriptions, there has been little change in the amount prescribed.
  • This demonstrates a need to develop and disseminate best practices for anorectal surgery, focusing on eliminating unnecessary opioid prescribing.


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Keller DS, Kenney BC, Harbaugh CM, Waljee JF, Brummett CM. A national evaluation of opioid prescribing and persistent use after ambulatory anorectal surgery. Surgery. Published Online 4 December 2020. DOI: https://doi.org/10.1016/j.surg.2020.11.006