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Endovascular surgery is not protective against new persistent opioid use development compared to open vascular surgery

  • Among opioid-naïve patients undergoing vascular surgery procedures in Medicare between 2009 and 2017, 2.6% of all patients developed new persistent use.
  • Undergoing endovascular carotid or venous surgery was associated with an increased risk of NPOU, whereas no differences were found between endovascular and open approaches for peripheral arterial or aortic disease.


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Brown CS; Osborne NH; Hu HM; Coleman D; Englesbe MJ; Waljee JF; Brummett CM; Vemuri C. Endovascular surgery is not protective against new persistent opioid use development compared to open vascular surgery. Vascular. Published online 15 June 2021. DOI: 10.1177/17085381211024514