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New Persistent Opioid Use after Acute Opioid Prescribing in Pregnancy

  • 0% of pregnant women filled an opioid prescription during pregnancy, and 4.0% of the women who filled developed new persistent opioid use.
  • Having a non-delivery procedure in pregnancy and having an emergency room visit during pregnancy are factors associated with filling an opioid in pregnancy
  • Filling a peripartum opioid prescription (1 week prior to or 3 days post-discharge) was significantly associated with new persistent opioid use.


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Peahl AF, Morgan DM, Dalton VK, et al. New persistent opioid use after acute opioid prescribing in pregnancy: a nationwide analysis [published online ahead of print, 2020 Mar 23]. Am J Obstet Gynecol. 2020;S0002-9378(20)30342-2. doi:10.1016/j.ajog.2020.03.020