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New Persistent Opioid Use Among Patients with Cancer After Curative-Intent Surgery

  • 4% of cancer patients not on opioids prior to a curative-intent surgery fill prescriptions at daily doses similar to chronic opioid users one year after surgery.
  • New persistent opioid use in patients receiving adjuvant chemotherapy is consistently higher than in those with no chemotherapy across different procedures.
  • Changing prescribing guidelines and patient counseling in the surveillance and survivorship phases of care may reduce new persistent opioid use among cancer patients after surgery.


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Lee JS, Hu HM, Edelman AL, et al. New Persistent Opioid Use Among Patients With Cancer After Curative-Intent Surgery. J Clin Oncol. 2017;35(36):4042-4049. doi:10.1200/JCO.2017.74.1363