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Probability of Opioid Prescription Refilling After Surgery: Does Initial Prescription Dose Matter?

  • Approximately 9% of patients who were not using opioids preoperatively refilled an opioid prescription after surgery.
  • The probability of a patient refilling a postoperative opioid prescription was not correlated with their initial prescription strength.
  • Surgeons could prescribe smaller opioid prescriptions without influencing the probability of a refill request.


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Sekhri S, Arora NS, Cottrell H, et al. Probability of Opioid Prescription Refilling After Surgery: Does Initial Prescription Dose Matter?. Ann Surg. 2018;268(2):271-276. doi:10.1097/SLA.0000000000002308