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Rate of Opioid Prescriptions for Patients With Acute Ankle Sprain

  • Among opioid na├»ve patients who did not fill an opioid prescription one year before sprain diagnosis, 8.3% filled an opioid prescription within 7 days of diagnosis, and, in this group, the rate of new, persistent opioid use (filled an opioid prescription 91 to 180 days after diagnosis and initial opioid exposure) was 8.4%.
  • The most commonly prescribed opioid was hydrocodone (62.3%), followed by tramadol (15.6%) and oxycodone (11.5%).
  • Most prescriptions were provided by physicians (77.4%) and advanced practice providers (18.9%) in emergency medicine and primary care settings.


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Finney FT, Gossett TD, Hu HM, et al. Rate of Opioid Prescriptions for Patients With Acute Ankle Sprain. Ann Intern Med. 2019;171(6):441-443. doi:10.7326/M19-0679