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Spillover Effect of Evidence-Based Postoperative Opioid Prescribing

  • After introducing evidence-based prescribing recommendations for laparoscopic cholecystectomy, prescribing decreased for four other surgical procedures, with no significant increase in refill requests.
  • Implementing evidence-based prescribing recommendations contributes to increased awareness of safe and appropriate opioid prescribing practices.


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Howard R, Alameddine M, Klueh M, et al. Spillover Effect of Evidence-Based Postoperative Opioid Prescribing [published correction appears in J Am Coll Surg. 2019 Apr;228(4):720]. J Am Coll Surg. 2018;227(3):374-381. doi:10.1016/j.jamcollsurg.2018.06.007