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The Association Between Preoperative Opioid Exposure and Prolonged Postoperative Use

  • 41% of patients had nonchronic, periodic opioid fills in the year prior to general, gynecologic, and urologic surgical procedures.
  • Patterns of preoperative fills were most strongly associated with persistent postoperative opioid use. Patients with recent intermittent use were significantly more likely to have prolonged fills after surgery compared with opioid-naïve patients
  • Identifying opioid use before surgery is a critical opportunity to optimize care after surgery.


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Katzman C, Harker EC, Ahmed R, et al. The Association Between Preoperative Opioid Exposure and Prolonged Postoperative Use [published online ahead of print, 2020 May 18]. Ann Surg. 2020; doi:10.1097/SLA.0000000000003723