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Persistent Opioid Use After Ophthalmic Surgery in Opioid-Naïve Patients and Associated Risk Factors

Ung C; Yonekawa Y; Waljee JF; Gunaseelan V; Lai Y; Woodward MA. Persistent Opioid Use After Ophthalmic Surgery in Opioid-Naïve Patients and Associated Risk Factors. Ophthalmology. Published online 22 April 2021. DOI: https://doi.org/10.1016/j.ophtha.2021.04.021

  • Exposure to opioids in the perioperative period is associated with new persistent use in patients who were previously opioid-naïve. New persistent opioid use was higher in patients having an initial perioperative opioid fill (3.4%) than patients without an initial perioperative fill (0.6%).
  • After adjusting for patient characteristics, initial perioperative opioid fill was independently associated with an increased odds of new persistent use.
  • Surgeons should be aware of those risks to identify at-risk patients in the current national opioid crisis and minimize prescribing opioids when possible.


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