- Preoperative opioid use was correlated with an increased mortality within 90 days after surgery
- Patients with high and medium preoperative opioid exposure were more likely to die within 90 days after outpatient surgery compared with opioid-naïve patients
- Mortality did not differ between opioid-naïve patients and patients with low preoperative opioid exposure.
Santosa KB, Lai Y, Oliver JD, et al. Preoperative Opioid Use and Mortality After Minor Outpatient Surgery. JAMA Surg. Published online October 21, 2020. doi:10.1001/jamasurg.2020.3623