Our Evidence
OPEN is driven by data and evidence. Our Prescribing Recommendations and all of our educational materials are shaped by our team’s research and published papers.
Healthcare Professionals
We support you with evidence-based practices, opioid prescribing recommendations, and more.
Piloting a statewide emergency department take-home naloxone program: Improving the quality of care for patients at risk of opioid overdose
Dora-Laskey, A., Kellenberg, J., Dahlem, C.H., English, E., Walker, M. G., Brummett, C.M., Kocher, K.E. Published online 28 December, 2021 https://doi.org/10.1111/acem.14435- More than 140 providers were trained in the use of medications for OUD in acute care settings.
- A total of 872 naloxone rescue kits were distributed to ED patients at risk of opioid overdose during the first phase of this project.
- A statewide ED take-home naloxone program was shown to be feasible across a range of different hospitals with varying maturity in preexisting OUD resources and capabilities.
Association of Opioid Overdose Risk Factors and Naloxone Prescribing in US Adults
Lin LA, Brummett CM, Waljee JF, Englesbe MJ, Gunaseelan V, Bohnert ASB. Association of Opioid Overdose Risk Factors and Naloxone Prescribing in US Adults. J Gen Intern Med. 2020;35(2):420-427. doi:10.1007/s11606-019-05423-7- While there is a growing prevalence of naloxone fills among insured U.S. adults receiving opioids, overall prevalence of naloxone prescribing remains extremely low.
- Key factors associated with opioid overdose risk were also associated with receiving naloxone. However, history of overdose was not associated with filling of a naloxone prescription.
- Substantial further work is needed to increase naloxone access for patients at risk for opioid overdose.