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Statewide Implementation of Postoperative Opioid Prescribing Guidelines

  • Evidence-based prescribing guidelines reduced postoperative opioid prescription size across a statewide population without negatively affecting patient satisfaction or pain
  • Despite the reductions in prescription size and opioid use, there were no clinically important changes in satisfaction or pain scores
  • Mean prescription size decreased by 8 pills after the guidelines were released and opioid consumption also decreased by 3 pills


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    Vu JV, Howard RA, Gunaseelan V, Brummett CM, Waljee JF, Englesbe MJ. Statewide Implementation of Postoperative Opioid Prescribing Guidelines. N Engl J Med. 2019;381(7):680-682. doi:10.1056/NEJMc1905045